On 2 occasions now my 08 Prius battery has died mysteriously and quickly. The circumstances were similar both times. I'd been driving in a parking lot for a while searching for a space. Then parked for about 15 minutes. Then started the car, but decided instead I needed to make a phone call. Maybe started the call while it was still running, but then turned car off (don't remember for sure). It was hot & the call was taking a while, so I rolled down the windows half way on driver & passenger sides. Then opened driver door for more air flow. After about ten minutes, I go to the start the car and it's DEAD! Both times had to call AAA to get a jump. After the first incidence I took it to Toyota dealer to check the battery, they said it was fine. Is there some bad combination of open door (light on), headlights on, bluetooth, proximity key & an ipod cable (just the cable) plugged into console that could cause the battery to drain in ten minutes???
You can test your 12 volt via http://priuschat.com/forums/newbie-forum/73400-weird-stuff-happening-mpgs-dropping-test-battery.html. Best to do it after the car has sat overnight. Leaving your car in ACC mode will drain your 12 volt battery. Leaving it in IG-ON (not READY) will drain it very rapidly. If you're want to sit with the accessories on for very long, put it in READY mode.
Have you replace the 12V yet? Problem is, it takes so long for the car to charge it, that a jump and go leaves you at high risk for having it go dead again. Best approach is to trickle charge the battery for several hours at 2-4 amps. If it dies again, just bite the bullet and get a new one.