disable key fob due to stolen registration

Hello all. Is possible to disable the unlock button on the key fob so that car doesn't open. I know about the button (SKS) under the steering wheel, but that just deactivates the function of bringing the key close to the car to unlock the doors, and being able to start the car without pluging the key in. But I'm still able to unlock/lock the car by pressing unlock/lock on the key fob. I'm trying to deactivate the function where the key fob can unlock/lock the car totally for any key fob, mine or a clone. I understand I will probably have to get a new cylinder/physical key for the door as well.

Thank you,
Eric

Gen 2 Prius