When I post a reply the cursor changes to "working..." and stays there. If I manually refresh the page I see that my post has been published. I vaguely remember members posting similar problems a year or two ago. Macintosh OS X 10.5.6 A week or so ago I briefly tried the Chrome 10.x beta, but never replaced the Chrome version I had been, and am now still using.
Odd... sounds like a problem with the javascript that does the "Quick Reply". Perhaps it didn't fully download or something? Can you scrub your cache and see if that helps?