Every now and then, something will show up in my mailing lists that is exceptional: The latest research from Nature: 17 September 2020 Volume 585 Issue 7825 A pandemic is no time to cut the European Research Council’s funding Keep collaboration open when doors are closing WORLD VIEW Study the role of hubris in nations’ COVID-19 response Martha Lincoln RESEARCH HIGHLIGHTS This issue's Research Highlights Selections from the scientific literature. Parenting brain switch, vanishing journals and COVID-19 in kids NEWS Scientists relieved as coronavirus vaccine trial restarts — but question lack of transparency David Cyranoski, Smriti Mallapaty The underdog coronavirus vaccines that the world will need if front runners stumble Ewen Callaway US university workers fight a return to campus as COVID-19 cases grow Emma Marris US political crackdown spurs fears of Chinese brain-drain Andrew Silver The Arctic is burning like never before — and that’s bad news for climate change Alexandra Witze FEATURES The lasting misery of coronavirus long-haulers Michael Marshall How COVID-19 can damage the brain Michael Marshall MULTIMEDIA Genes chart Vikings' spread across Europe Mapping the migration of the Vikings, and the world’s smallest ultrasound device. The European Research Council (ERC) presents “COVID-19: Spotlight on Frontier Research” - free online session, moderated by Nature’s editor-in-chief Magdalena Skipper, with four top scientists who bring innovative, sometimes unexpected, solutions to coronavirus health crisis. Join the event in virtual hub 10 at the EU R&I Days on Tuesday 22 September. Register at https://research-innovation-days.ec.europa.eu/register The lifelong studies that hold clues to what today’s kids might have in store Barbara Maughan The poisonous history of chemotherapy Heidi Ledford Scientists use big data to sway elections and predict riots — welcome to the 1960s Jill Lepore Coronavirus diaries: give your brain a break from science busywork, it deserves it John Tregoning Don’t be a prig in peer review Jeff C. Clements WHERE I WORK From high-altitude balloons to Moon missions James Mitchell Crow Red blood cell tension protects against severe malaria in the Dantu blood group The rare blood group Dantu is known to protect against severe malaria, and a mechanism is proposed here: Dantu red blood cells have a high membrane tension that prevents invasion by malaria parasites. Silvia N. Kariuki, Alejandro Marin-Menendez, Viola Introini et al. Evolution of the endothelin pathway drove neural crest cell diversification CRISPR–Cas9-mediated disruption of the endothelin signalling pathway in the sea lamprey Petromyzon marinusand the frog Xenopus laevis were used to delineate ancient and lineage-specific roles of endothelin signalling and provide insights into vertebrate evolution. Tyler A. Square, David Jandzik, James L. Massey et al. Homeostatic mini-intestines through scaffold-guided organoid morphogenesis Miniature gut tubes grown in vitro from mouse intestinal stem cells are perfusable, can be colonized with microorganisms and exhibit a similar arrangement and diversity of specialized cell types to intestines in vivo. Mikhail Nikolaev, Olga Mitrofanova, Nicolas Broguiere et al. The brain rhythms that detach us from reality The rhythmic activity of a single layer of neurons has now been shown to cause dissociation — an experience involving a feeling of disconnection from the surrounding world. Ken Solt, Oluwaseun Akeju Prokaryotic viperins produce diverse antiviral molecules Aude Bernheim, Adi Millman, Gal Ofir et al. Deep posteromedial cortical rhythm in dissociation Dissociative states in mouse and human brains are traced to low-frequency rhythmic neural activity—with distinct molecular, cellular and physiological properties—in the deep retrosplenial cortex and the posteromedial cortex. Sam Vesuna, Isaac V. Kauvar, Ethan Richman et al. Reprogramming roadmap reveals route to human induced trophoblast stem cells A single-cell transcriptomics roadmap of human dermal fibroblasts reprogrammed to primed and naive pluripotency reveals a route for the direct reprogramming of somatic cells into induced trophoblast stem cells. Xiaodong Liu, John F. Ouyang, Fernando J. Rossello et al. Metabolic trait diversity shapes marine biogeography A tight coupling between metabolic rate, efficacy of oxygen supply and the temperature sensitivities of marine animals predicts a variety of geographical niches that better aligns with the distributions of species than models of either temperature or oxygen alone. Curtis Deutsch, Justin L. Penn, Brad Seibel Bridging of DNA breaks activates PARP2–HPF1 to modify chromatin The PARP2–HPF1 histone-modifying complex bridges two nucleosomes to align broken DNA ends for ligation, initiating conformational changes that activate PARP2 and enable DNA damage repair. Silvija Bilokapic, Marcin J. Suskiewicz, Ivan Ahel et al. Plasticity of ether lipids promotes ferroptosis susceptibility and evasion The cellular organelles peroxisomes contribute to the sensitivity of cells to ferroptosis by synthesizing polyunsaturated ether phospholipids, and changes in the abundances of these lipids are associated with altered sensitivity to ferroptosis during cell-state transitions. Yilong Zou, Whitney S. Henry, Emily L. Ricq et al. Stimulus-specific hypothalamic encoding of a persistent defensive state Persistent neural activity in the mouse hypothalamus encodes aversive emotional states related to specific threatening stimuli. Ann Kennedy, Prabhat S. Kunwar, Ling-yun Li et al. Both naive and memory B cells respond to flu vaccine Influenza vaccination induces a protective memory immune response. The finding that human naive and memory B cells enter vaccine-induced germinal-centre structures suggests that both cell types aid this memory response. Lauren B. Rodda, Marion Pepper Structural basis for the action of the drug trametinib at KSR-bound MEK Zaigham M. Khan, Alexander M. Real, William M. Marsiglia et al. NEWS & VIEWS Light-activated neurons deep in the brain control body heat Gary J. Schwartz Developing cells remember where they came from, thanks to keratin filaments Mateusz Trylinski, Buzz Baum Planet discovered transiting a dead star ... Bob Wilson
I also found this on Nature's home page: https://www.nature.com/articles/d41586-020-02672-z PNAS, Nature, and Science weekly issues come out Wednesday, Thursday, and Friday respectively. One could do worse in terms of web crawling.
A troublemaker might send charcoal samples from ... several Asian countries to that Thunen Wood Institute guy, just out of curiosity.
