THe computer on our HCH consistently shows about 1.5 MPG lower than calculated at fill-up. This weekend I will check the odometer on the interstate. Once you have the odometer error, the calculated mileage is the final word. Frankly, I don't think neither Toyota nor Honda spend that much time ensuring their computers show exactly the right consumption!
Update: My last two tanks averaged about 44 to 45 MPG according to the computer... but I calculated my last tank at 48+ MPG!!!! WOOO HOOO!!!!